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P2RX7: Expression Responds to Sleep Deprivation and Associates with Rapid Cycling in Bipolar Disorder Type 1

CONTEXT: Rapid cycling is a severe form of bipolar disorder with an increased rate of episodes that is particularly treatment-responsive to chronotherapy and stable sleep-wake cycles. We hypothesized that the P2RX7 gene would be affected by sleep deprivation and be implicated in rapid cycling. OBJEC...

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Détails bibliographiques
Auteurs principaux: Backlund, Lena, Lavebratt, Catharina, Frisén, Louise, Nikamo, Pernilla, Hukic Sudic, Dzana, Träskman-Bendz, Lil, Landén, Mikael, Edman, Gunnar, Vawter, Marquis P., Ösby, Urban, Schalling, Martin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429455/
https://ncbi.nlm.nih.gov/pubmed/22952630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043057
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