Pravastatin-induced improvement in coronary reactivity and circulating ATP and ADP levels in young adults with type 1 diabetes

Aims: Extracellular ATP and ADP regulate diverse inflammatory, prothrombotic and vasoactive responses in the vasculature. Statins have been shown to modulate their signaling pathways in vitro. We hypothesized that altered intravascular nucleotide turnover modulates vasodilation in patients with type...

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Autori principali: Kiviniemi, Tuomas O., Yegutkin, Gennady G., Toikka, Jyri O., Paul, Subhadeep, Aittokallio, Tero, Janatuinen, Tuula, Knuuti, Juhani, Rönnemaa, Tapani, Koskenvuo, Juha W., Hartiala, Jaakko J., Jalkanen, Sirpa, Raitakari, Olli T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2012
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429103/
https://ncbi.nlm.nih.gov/pubmed/22934084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00338
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