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IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells

Although very high levels of interleukin (IL)-1β are present in the intestines of patients suffering from inflammatory bowel diseases (IBD), little is known about the contribution of IL-1β to intestinal pathology. Here, we used two complementary models of chronic intestinal inflammation to address t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Coccia, Margherita, Harrison, Oliver J., Schiering, Chris, Asquith, Mark J., Becher, Burkhard, Powrie, Fiona, Maloy, Kevin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428945/
https://ncbi.nlm.nih.gov/pubmed/22891275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111453
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