Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions

AIMS: An association between carbamazepine-induced hypersensitivity and HLA-A*3101 has been reported in populations of both European and Asian descent. We aimed to investigate HLA-A*3101 and other common variants across the genome as markers for cutaneous adverse drug reactions (cADRs) attributed to...

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Main Authors: McCormack, Mark, Urban, Thomas J, Shianna, Kevin V, Walley, Nicole, Pandolfo, Massimo, Depondt, Chantal, Chaila, Elijah, O’Conner, Gerard D, Kasperavičiūtė, Dalia, Radtke, Rodney A, Heinzen, Erin L, Sisodiya, Sanjay M, Delanty, Norman, Cavalleri, Gianpiero L
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428903/
https://ncbi.nlm.nih.gov/pubmed/22379998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.11.165
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