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Granulocyte Macrophage Colony Stimulating Factor Treatment of a Patient in Myasthenic Crisis: Effects on Regulatory T cells

INTRODUCTION: We describe a patient with a prolonged myasthenic crisis refractory to conventional immunomodulatory treatments who was treated with GM-CSF (granulocyte macrophage colony stimulating factor, sargramostim). METHODS: T regulatory cell (Tregs) suppressive function and Foxp3 expression wer...

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Bibliographic Details
Main Authors: Rowin, Julie, Thiruppathi, Muthusamy, Arhebamen, Ebinehita, Sheng, Jianrong, Prabhakar, Bellur S., Meriggioli, Matthew N.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428740/
https://ncbi.nlm.nih.gov/pubmed/22907239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.23488
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