TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation

Autophagy is a fundamental biological process of the eukaryotic cell contributing to diverse cellular and physiological functions including cell-autonomous defense against intracellular pathogens. Here we screened the Rab family of membrane trafficking regulators for effects on autophagic eliminatio...

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Main Authors: Pilli, Manohar, Arko-Mensah, John, Ponpuak, Marisa, Roberts, Esteban, Master, Sharon, Mandell, Michael, Dupont, Nicolas, Ornatowski, Wojciech, Jiang, Shanya, Bradfute, Steven, Bruun, Jack-Ansgar, Hansen, Tom Egil, Johansen, Terje, Deretic, Vojo
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428731/
https://ncbi.nlm.nih.gov/pubmed/22921120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.04.015
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