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Lung Function Measurements in Rodents in Safety Pharmacology Studies

The ICH guideline S7A requires safety pharmacology tests including measurements of pulmonary function. In the first step – as part of the “core battery” – lung function tests in conscious animals are requested. If potential adverse effects raise concern for human safety, these should be explored in...

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Autore principale: Hoymann, Heinz Gerd
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428707/
https://ncbi.nlm.nih.gov/pubmed/22973226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00156
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