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Lung Function Measurements in Rodents in Safety Pharmacology Studies
The ICH guideline S7A requires safety pharmacology tests including measurements of pulmonary function. In the first step – as part of the “core battery” – lung function tests in conscious animals are requested. If potential adverse effects raise concern for human safety, these should be explored in...
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| Format: | Artigo |
| Jezik: | Inglês |
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Frontiers Research Foundation
2012
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428707/ https://ncbi.nlm.nih.gov/pubmed/22973226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00156 |
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