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Genome-wide identification of significant aberrations in cancer genome

BACKGROUND: Somatic Copy Number Alterations (CNAs) in human genomes are present in almost all human cancers. Systematic efforts to characterize such structural variants must effectively distinguish significant consensus events from random background aberrations. Here we introduce Significant Aberrat...

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Detalhes bibliográficos
Main Authors: Yuan, Xiguo, Yu, Guoqiang, Hou, Xuchu, Shih, Ie-Ming, Clarke, Robert, Zhang, Junying, Hoffman, Eric P, Wang, Roger R, Zhang, Zhen, Wang, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428679/
https://ncbi.nlm.nih.gov/pubmed/22839576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-342
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