Effect of VEGF-targeted antisense gene therapy on retinoblastoma cell line SO-RB50 in vitro and in vivo

AIM: To evaluate the possibility of generation 4 polyamidoamine (G4PAMAM) dendrimers acting as the delivery system of vascular endothelial growth factor (VEGF) antisense oligodeoxynucleotides (VEGFASODN), and to investigate the anti-tumor effect of G4PAMAM/VEGFASODN complex on the cultured cells and...

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Detalhes bibliográficos
Main Authors: Xin, Guo-Hong, Zhao, Xin-Han, Liu, Dong, Gong, Qiang, Hou, Lei, Li, Jing-Yun, Pan, Bo-Rong, Li, Xu, Cheng, Ya-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2012
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428538/
https://ncbi.nlm.nih.gov/pubmed/22937502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2012.04.07
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