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The spectrum of RB1 germ-line mutations in hereditary retinoblastoma.

We have searched for germ-line RB1 mutations in 119 patients with hereditary retinoblastoma. Previous investigations by Southern blot hybridization and PCR fragment-length analysis had revealed mutations in 48 patients. Here we report on the analysis of the remaining 71 patients. By applying heterod...

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Detalhes bibliográficos
Main Authors: Lohmann, D. R., Brandt, B., Höpping, W., Passarge, E., Horsthemke, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914612/
https://ncbi.nlm.nih.gov/pubmed/8651278
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