Evaluation of an Enzyme-Linked Immunosorbent Assay Based on Crude Leishmania Histone Proteins for Serodiagnosis of Human Infantile Visceral Leishmaniasis

Human visceral leishmaniasis (VL) is routinely diagnosed by detecting IgG that specifically binds to Leishmania antigens. The enzyme-linked immunosorbent assay (ELISA) remains a widely used method. However, the biggest challenge remains the choice of antigen with the highest specificity and sensitiv...

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Главные авторы: Lakhal, Sami, Mekki, Salima, Ben-Abda, Imène, Mousli, Mohamed, Amri, Fethi, Aoun, Karim, Bouratbine, Aïda
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
Предметы:
Diagnostic Laboratory Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428402/
https://ncbi.nlm.nih.gov/pubmed/22815147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00257-12
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