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Evaluation of an Enzyme-Linked Immunosorbent Assay Based on Crude Leishmania Histone Proteins for Serodiagnosis of Human Infantile Visceral Leishmaniasis

Human visceral leishmaniasis (VL) is routinely diagnosed by detecting IgG that specifically binds to Leishmania antigens. The enzyme-linked immunosorbent assay (ELISA) remains a widely used method. However, the biggest challenge remains the choice of antigen with the highest specificity and sensitiv...

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Autori principali: Lakhal, Sami, Mekki, Salima, Ben-Abda, Imène, Mousli, Mohamed, Amri, Fethi, Aoun, Karim, Bouratbine, Aïda
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428402/
https://ncbi.nlm.nih.gov/pubmed/22815147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00257-12
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