Primary Human Airway Epithelial Cell-Dependent Inhibition of Human Lung Mast Cell Degranulation

INTRODUCTION: Chronic mast cell activation is a characteristic feature of asthma. BEAS-2B human airway epithelial cells (AEC) profoundly inhibit both constitutive and IgE-dependent human lung mast cell (HLMC) histamine release. The aim of this study was to examine the regulation of HLMC degranulatio...

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Detalhes bibliográficos
Main Authors: Martin, Neil, Ruddick, Andrew, Arthur, Greer K., Wan, Heidi, Woodman, Lucy, Brightling, Christopher E., Jones, Don J. L., Pavord, Ian D., Bradding, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428358/
https://ncbi.nlm.nih.gov/pubmed/22970103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043545
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