Mast Cells Promote Airway Smooth Muscle Cell Differentiation via Autocrine Up-Regulation of TGF-β1()

Asthma is a major cause of morbidity and mortality worldwide. It is characterized by airway dysfunction and inflammation. A key determinant of the asthma phenotype is infiltration of airway smooth muscle bundles by activated mast cells. We hypothesized that interactions between these cells promotes...

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Main Authors: Woodman, Lucy, Siddiqui, Salman, Cruse, Glenn, Sutcliffe, Amanda, Saunders, Ruth, Kaur, Davinder, Bradding, Peter, Brightling, Christopher
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992381/
https://ncbi.nlm.nih.gov/pubmed/18802103
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