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Early Emergence and Selection of a SIV-LTR C/EBP Site Variant in SIV-Infected Macaques That Increases Virus Infectivity

CCAAT/enhancer binding protein (C/EBP)β, and C/EBP binding sites in the HIV/SIV- long terminal repeat (LTR) are crucial for regulating transcription and for IFNβ-mediated suppression of virus replication in macrophages, the predominant source of productive virus replication in the brain. We investig...

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Detalhes bibliográficos
Main Authors: Ravimohan, Shruthi, Gama, Lucio, Engle, Elizabeth L., Zink, M. Christine, Clements, Janice E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428313/
https://ncbi.nlm.nih.gov/pubmed/22952612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042801
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