Aberrant CD40-Induced NF-κB Activation in Human Lupus B Lymphocytes

Auto-reactive B lymphocytes and its abnormal CD40 signaling play important roles in the pathogenesis of systemic lupus erythematosus (SLE). In this study, we analyzed CD40 expression and CD40/CD154 induced activation of NF-κB signaling pathway in B cells from SLE patients. B cells from healthy volun...

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Main Authors: Zhang, Wen, Shi, Qun, Xu, Xiaotian, Chen, Hua, Lin, Wei, Zhang, Fengchun, Zeng, Xiaofeng, Zhang, Xuan, Ba, Denian, He, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428310/
https://ncbi.nlm.nih.gov/pubmed/22952582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041644
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