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Bax-derived membrane-active peptides act as potent and direct inducers of apoptosis in cancer cells
Although many cancer cells are primed for apoptosis, they usually develop resistance to cell death at multiple levels. Permeabilization of the outer mitochondrial membrane, which is mediated by proapoptotic Bcl-2 family members like Bax, is considered as a point-of-no-return for initiating apoptotic...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428271/ https://ncbi.nlm.nih.gov/pubmed/21245196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.076745 |
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