Bax-derived membrane-active peptides act as potent and direct inducers of apoptosis in cancer cells

Although many cancer cells are primed for apoptosis, they usually develop resistance to cell death at multiple levels. Permeabilization of the outer mitochondrial membrane, which is mediated by proapoptotic Bcl-2 family members like Bax, is considered as a point-of-no-return for initiating apoptotic...

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Detaylı Bibliyografya
Asıl Yazarlar: Valero, Juan Garcia, Sancey, Lucie, Kucharczak, Jérôme, Guillemin, Yannis, Gimenez, Diana, Prudent, Julien, Gillet, Germain, Salgado, Jesús, Coll, Jean-Luc, Aouacheria, Abdel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428271/
https://ncbi.nlm.nih.gov/pubmed/21245196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.076745
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