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Effect of cell-penetrating peptide-coated nanostructured lipid carriers on the oral absorption of tripterine

PURPOSE: To develop nanostructured-lipid carriers (NLCs) coated with cell-penetrating peptides (CPP) for improving the oral bioavailability of tripterine. METHODS: We prepared CPP-coated tripterine-loaded NLCs (CT-NLCs) by using a solvent evaporation method, and determined their physical properties....

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Détails bibliographiques
Auteurs principaux: Chen, Yan, Yuan, Ling, Zhou, Lei, Zhang, Zhen-hai, Cao, Wei, Wu, Qingqing
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428248/
https://ncbi.nlm.nih.gov/pubmed/22942642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S34991
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