Formulation, characterization, and evaluation of in vitro skin permeation and in vivo pharmacodynamics of surface-charged tripterine-loaded nanostructured lipid carriers

BACKGROUND: Nanostructured lipid carriers (NLCs) are attractive materials for topical drug delivery, and in a previous study, we demonstrated that NLCs loaded with tripterine enhance its deposition. However, the surface charge of nanoparticles influences percutaneous drug penetration. Therefore, we...

Full description

Saved in:
Bibliographic Details
Main Authors: Chen, Yan, Zhou, Lei, Yuan, Ling, Zhang, Zhen-hai, Liu, Xuan, Wu, Qingqing
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392146/
https://ncbi.nlm.nih.gov/pubmed/22787398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S32476
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items