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YcaO domains utilize ATP to activate amide backbones during peptide cyclodehydrations
Thiazole/oxazole-modified microcins (TOMMs) encompass a recently defined class of ribosomally synthesized natural products with a diverse set of biological activities. Although TOMM biosynthesis has been investigated for over a decade, the mechanism of heterocycle formation by the synthetase enzymes...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428213/ https://ncbi.nlm.nih.gov/pubmed/22522320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.944 |
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