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Mouse model reveals the role of SOX7 in the development of congenital diaphragmatic hernia associated with recurrent deletions of 8p23.1

Recurrent microdeletions of 8p23.1 that include GATA4 and SOX7 confer a high risk of both congenital diaphragmatic hernia (CDH) and cardiac defects. Although GATA4-deficient mice have both CDH and cardiac defects, no humans with cardiac defects attributed to GATA4 mutations have been reported to hav...

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Autori principali: Wat, Margaret J., Beck, Tyler F., Hernández-García, Andrés, Yu, Zhiyin, Veenma, Danielle, Garcia, Monica, Holder, Ashley M., Wat, Jeanette J., Chen, Yuqing, Mohila, Carrie A., Lally, Kevin P., Dickinson, Mary, Tibboel, Dick, de Klein, Annelies, Lee, Brendan, Scott, Daryl A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428158/
https://ncbi.nlm.nih.gov/pubmed/22723016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds241
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