Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB–FKBPL–NOTCH4 region of chromosome 6p21.3

Age-related macular degeneration (AMD) is a leading cause of visual loss in Western populations. Susceptibility is influenced by age, environmental and genetic factors. Known genetic risk loci do not account for all the heritability. We therefore carried out a genome-wide association study of AMD in...

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Main Authors: Cipriani, Valentina, Leung, Hin-Tak, Plagnol, Vincent, Bunce, Catey, Khan, Jane C., Shahid, Humma, Moore, Anthony T., Harding, Simon P., Bishop, Paul N., Hayward, Caroline, Campbell, Susan, Armbrecht, Ana Maria, Dhillon, Baljean, Deary, Ian J., Campbell, Harry, Dunlop, Malcolm, Dominiczak, Anna F., Mann, Samantha S., Jenkins, Sharon A., Webster, Andrew R., Bird, Alan C., Lathrop, Mark, Zelenika, Diana, Souied, Eric H., Sahel, José-Alain, Léveillard, Thierry, Cree, Angela J., Gibson, Jane, Ennis, Sarah, Lotery, Andrew J., Wright, Alan F., Clayton, David G., Yates, John R.W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2012
Ábhair:
Association Studies Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428154/
https://ncbi.nlm.nih.gov/pubmed/22694956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds225
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