Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy

Dystroglycan is a transmembrane glycoprotein that links the extracellular basement membrane to cytoplasmic dystrophin. Disruption of the extensive carbohydrate structure normally present on α-dystroglycan causes an array of congenital and limb girdle muscular dystrophies known as dystroglycanopathie...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beedle, Aaron M., Turner, Amy J., Saito, Yoshiaki, Lueck, John D., Foltz, Steven J., Fortunato, Marisa J., Nienaber, Patricia M., Campbell, Kevin P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428090/
https://ncbi.nlm.nih.gov/pubmed/22922256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63004
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