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Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy
Dystroglycan is a transmembrane glycoprotein that links the extracellular basement membrane to cytoplasmic dystrophin. Disruption of the extensive carbohydrate structure normally present on α-dystroglycan causes an array of congenital and limb girdle muscular dystrophies known as dystroglycanopathie...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428090/ https://ncbi.nlm.nih.gov/pubmed/22922256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63004 |
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