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The use of s-2-cyanoethyl phosphorothioate in the preparation of oligo 5'-deoxy-5'-thiothymidylates.

An improvement of our strategy for the stepwise synthesis of oligo 5'-deoxy-5'-thiodeoxyribonucleotides [Chladek and Nagyvary (1972) J. Amer. Chem. Soc. 94, 2079] involves the use of 5'-O-tosylthymidine 3'-S-2-cyanoethyl phosphorothioate. The displacement of the tosylate by thymi...

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Dettagli Bibliografici
Autori principali: Kresse, J, Nagpal, K L, Nagyvary, J, Uchic, J T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1975
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC342807/
https://ncbi.nlm.nih.gov/pubmed/1129142
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