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The cDNA-derived investigational human parainfluenza virus type 3 vaccine rcp45 is well-tolerated, infectious, and immunogenic in infants and young children

BACKGROUND: Human parainfluenza virus type 3 (HPIV3) is an important yet underappreciated cause of lower respiratory tract illness in children, and a licensed vaccine is not yet available. METHODS: A live-attenuated investigational HPIV3 vaccine virus designated rcp45 was derived from cDNA using rev...

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Hlavní autoři: Karron, Ruth A., Casey, Roberta, Thumar, Bhagvanji, Surman, Sonja, Murphy, Brian R., Collins, Peter L., Schmidt, Alexander C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428040/
https://ncbi.nlm.nih.gov/pubmed/21829138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0b013e31822ea24f
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