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Proapoptotic effects of novel pentabromobenzylisothioureas in human leukemia cell lines

A series of new pentabromobenzylisothioureas [ZKK-1–ZKK-5; (ZKKs)] carrying additional substituents on nitrogen atoms has been synthesized. The ZKKs were found to induce apoptosis in HL-60 (human promyleocytic leukemia) and K-562 (human chronic erythromyeloblastoid leukemia) cell lines in a concentr...

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Detalhes bibliográficos
Main Authors: Koronkiewicz, Mirosława, Chilmonczyk, Zdzisław, Kazimierczuk, Zygmunt
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427706/
https://ncbi.nlm.nih.gov/pubmed/22942618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-011-9841-8
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