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Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β

BACKGROUND: Matrix metalloproteinases are catabolic enzymes that play a key role in the articular cartilage degeneration evident in degenerative and inflammatory conditions of articular cartilage. The aim of this study is to assess the ability of pravastatin to modify matrix metalloproteinase (MMP)...

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書目詳細資料
Main Authors: Baker, Joseph F., Walsh, Pauline M., Byrne, Damien P., Mulhall, Kevin J.
格式: Artigo
語言:Inglês
出版: Springer International Publishing 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427703/
https://ncbi.nlm.nih.gov/pubmed/22684544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10195-012-0200-4
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