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Implication of interleukin 18 in production of matrix metalloproteinases in articular chondrocytes in arthritis: direct effect on chondrocytes may not be pivotal

Objective: To clarify the effect of interleukin (IL) 18 on cartilage degeneration by studying the profile of IL18 receptor (IL18R) on chondrocytes and the direct effect of IL18 on production of matrix metalloproteinases (MMPs), aggrecanases, and tissue inhibitors of metalloproteinases (TIMPs) in art...

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Main Authors: Dai, S, Shan, Z, Nishioka, K, Yudoh, K
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755478/
https://ncbi.nlm.nih.gov/pubmed/15834055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.026088
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