Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β

BACKGROUND: Matrix metalloproteinases are catabolic enzymes that play a key role in the articular cartilage degeneration evident in degenerative and inflammatory conditions of articular cartilage. The aim of this study is to assess the ability of pravastatin to modify matrix metalloproteinase (MMP)...

Full description

Saved in:
Bibliographic Details
Main Authors: Baker, Joseph F., Walsh, Pauline M., Byrne, Damien P., Mulhall, Kevin J.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2012
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427703/
https://ncbi.nlm.nih.gov/pubmed/22684544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10195-012-0200-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items