Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β

BACKGROUND: Matrix metalloproteinases are catabolic enzymes that play a key role in the articular cartilage degeneration evident in degenerative and inflammatory conditions of articular cartilage. The aim of this study is to assess the ability of pravastatin to modify matrix metalloproteinase (MMP)...

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Bibliographische Detailangaben
Hauptverfasser: Baker, Joseph F., Walsh, Pauline M., Byrne, Damien P., Mulhall, Kevin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2012
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427703/
https://ncbi.nlm.nih.gov/pubmed/22684544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10195-012-0200-4
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