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Induction of Bcl-3 by acute binge alcohol results in Toll-like receptor 4/LPS tolerance
Acute alcohol binge results in immunosuppression and impaired production of proinflammatory cytokines, including TNF-α. TNF-α production is induced by LPS, a TLR4 ligand, and is tightly regulated at various levels of the signaling cascade, including the NF-κB transcription factor. Here, we hypothesi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Leukocyte Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427604/ https://ncbi.nlm.nih.gov/pubmed/22782967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0112050 |
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