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Explaining differences in the lifespan and replicative capacity of cells: a general model and comparative analysis of vertebrates

A better understanding of the factors that govern individual cell lifespan and the replicative capacity of cells (i.e. Hayflick's limit) is important for addressing disease progression and ageing. Estimates of cell lifespan in vivo and the replicative capacity of cell lines in culture vary subs...

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Detalhes bibliográficos
Main Authors: Gillooly, James F., Hayward, April, Hou, Chen, Burleigh, J. Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427577/
https://ncbi.nlm.nih.gov/pubmed/22810428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2012.1129
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