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Size matters in activation/inhibition of ligand-gated ion channels
Cys-loop, glutamate, and P2X receptors are ligand-gated ion channels (LGICs) with 5, 4, and 3 protomers, respectively. There is now growing atomic-level understanding of their gating mechanisms. Although each family is unique in the architecture of the ligand-binding pocket, the pathway for motions...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427461/ https://ncbi.nlm.nih.gov/pubmed/22789930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.06.005 |
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