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CFTR Regulates Early Pathogenesis of Chronic Obstructive Lung Disease in βENaC-Overexpressing Mice

BACKGROUND: Factors determining the onset and severity of chronic obstructive pulmonary disease remain poorly understood. Previous studies demonstrated that airway surface dehydration in βENaC-overexpressing (βENaC-Tg) mice on a mixed genetic background caused either neonatal mortality or chronic ob...

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Detalhes bibliográficos
Main Authors: Johannesson, Bjarki, Hirtz, Stephanie, Schatterny, Jolanthe, Schultz, Carsten, Mall, Marcus A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427321/
https://ncbi.nlm.nih.gov/pubmed/22937152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044059
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