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AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway
Pancreatic ductal adenocarcinoma (PDA), the fourth leading cause of cancer death in the United States, is a complex disease that arises in the setting of genetic alterations (KRAS, BRCA1, SMAD4, CDKN2A/p16(INK4a) and TP53), epigenetic perturbations (MIR155, acetylation and methylation) and epicellul...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427269/ https://ncbi.nlm.nih.gov/pubmed/22722139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20258 |
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