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Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease
Huntington disease (HD) is caused by an extended polyglutamine [poly(Q)] stretch in the Huntingtin (HTT) protein, and is associated with the accumulation of intracellular protein aggregates, onset of progressive chorea, psychiatric symptoms and dementia. Although the mechanism underlying the patholo...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Landes Bioscience
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427262/ https://ncbi.nlm.nih.gov/pubmed/22617512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20139 |
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