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Dual roles of Atg8−PE deconjugation by Atg4 in autophagy

Modification of target molecules by ubiquitin or ubiquitin-like (Ubl) proteins is generally reversible. Little is known, however, about the physiological function of the reverse reaction, deconjugation. Atg8 is a unique Ubl protein whose conjugation target is the lipid phosphatidylethanolamine (PE)....

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Detalhes bibliográficos
Main Authors: Yu, Zhong-Qiu, Ni, Tao, Hong, Bing, Wang, Hai-Yan, Jiang, Fen-Jun, Zou, Shenshen, Chen, Yong, Zheng, Xi-Long, Klionsky, Daniel J., Liang, Yongheng, Xie, Zhiping
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427254/
https://ncbi.nlm.nih.gov/pubmed/22652539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19652
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