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FunSAV: Predicting the Functional Effect of Single Amino Acid Variants Using a Two-Stage Random Forest Model

Single amino acid variants (SAVs) are the most abundant form of known genetic variations associated with human disease. Successful prediction of the functional impact of SAVs from sequences can thus lead to an improved understanding of the underlying mechanisms of why a SAV may be associated with ce...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Mingjun, Zhao, Xing-Ming, Takemoto, Kazuhiro, Xu, Haisong, Li, Yuan, Akutsu, Tatsuya, Song, Jiangning
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427247/
https://ncbi.nlm.nih.gov/pubmed/22937107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043847
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