The TT Genotype of the STAT4 rs7574865 Polymorphism Is Associated with High Disease Activity and Disability in Patients with Early Arthritis

BACKGROUND: The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis. In the present study, we investigated the effects of these genetic vari...

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Bibliographische Detailangaben
Hauptverfasser: Lamana, Amalia, Balsa, Alejandro, Rueda, Blanca, Ortiz, Ana M., Nuño, Laura, Miranda-Carus, Maria Eugenia, Gonzalez-Escribano, Maria F., Lopez-Nevot, Miguel A., Pascual-Salcedo, Dora, Martin, Javier, González-Álvaro, Isidoro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427144/
https://ncbi.nlm.nih.gov/pubmed/22937072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043661
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