The TT Genotype of the STAT4 rs7574865 Polymorphism Is Associated with High Disease Activity and Disability in Patients with Early Arthritis

BACKGROUND: The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis. In the present study, we investigated the effects of these genetic vari...

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Detalhes bibliográficos
Main Authors: Lamana, Amalia, Balsa, Alejandro, Rueda, Blanca, Ortiz, Ana M., Nuño, Laura, Miranda-Carus, Maria Eugenia, Gonzalez-Escribano, Maria F., Lopez-Nevot, Miguel A., Pascual-Salcedo, Dora, Martin, Javier, González-Álvaro, Isidoro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427144/
https://ncbi.nlm.nih.gov/pubmed/22937072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043661
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