Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice

Prion diseases are fatal neurodegenerative disorders that include bovine spongiform encephalopathy (BSE) and scrapie in animals and Creutzfeldt-Jakob disease (CJD) in humans. They are characterized by long incubation periods, variation in which is determined by many factors including genetic backgro...

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Autori principali: Grizenkova, Julia, Akhtar, Shaheen, Hummerich, Holger, Tomlinson, Andrew, Asante, Emmanuel A., Wenborn, Adam, Fizet, Jérémie, Poulter, Mark, Wiseman, Frances K., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Brandner, Sebastian, Collinge, John, Lloyd, Sarah E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427081/
https://ncbi.nlm.nih.gov/pubmed/22869728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208917109
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