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Photochemical production of psoralen - DNA monoadducts capable of subsequent photocrosslinking.
Irradiation of 4' -aminomethyl-4,5' ,8-trimethyl psoralen in the presence of DNA at wavelengths between 380 and 400nm leads to efficient production of monoadducts with no significant amount of crosslinking. The yield of monoadduct attainable is high (about 35 adducts per 1000 base pairs) a...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1978
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC342699/ https://ncbi.nlm.nih.gov/pubmed/724496 |
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