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Effect of histone acetylation on structure and in vitro transcription of chromatin.

n-Butyrate treatment of growing Hela cells produces a dramatic increase in the levels of histone acetylation. We have exploited this system to study the effect of histone acetylation on chromatin structure. Chromatin containing highly acetylated histones is more rapidly digested to acid-soluble mate...

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Detalhes bibliográficos
Main Authors: Mathis, D J, Oudet, P, Wasylyk, B, Chambon, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC342693/
https://ncbi.nlm.nih.gov/pubmed/724494
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