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Differential Cytokine Production and Bystander Activation of Autoreactive B Cells in Response to CpG-A and CpG-B ODNs

Synthetic oligonucleotides containing CpG motifs (CpG ODNs) have been shown to induce proliferation, differentiation and cytokine production in B cells, macrophages and DCs through a TLR9-dependent mechanism. A class (CpG-A) and B class (CpG-B) ODNs display distinct physical properties. CpG-A, but n...

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Detalhes bibliográficos
Main Authors: Avalos, Ana M., Latz, Eicke, Mousseau, Betty, Christensen, Sean R., Shlomchik, Mark J., Lund, Frances, Marshak-Rothstein, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426913/
https://ncbi.nlm.nih.gov/pubmed/19864612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901941
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