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A General One-pot, Two-step Protocol Accessing a Range of Novel Polycyclic Heterocycles with High Skeletal Diversity

An Ugi one-pot three-component 4-center reaction was coupled with a subsequent acid mediated cyclodehydration step to furnish a multitude of unique scaffolds having in common an embedded or attached benzimidazole and often a ring system formed through lactamization. Using combinations of tethered Ug...

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Hlavní autoři: Xu, Zhigang, Ayaz, Muhammad, Cappelli, Alexandra A., Hulme, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426865/
https://ncbi.nlm.nih.gov/pubmed/22746181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co300046r
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