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Rerouting Citrate Metabolism in Lactococcus lactis to Citrate-Driven Transamination

Oxaloacetate is an intermediate of the citrate fermentation pathway that accumulates in the cytoplasm of Lactococcus lactis ILCitM(pFL3) at a high concentration due to the inactivation of oxaloacetate decarboxylase. An excess of toxic oxaloacetate is excreted into the medium in exchange for citrate...

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Detalhes bibliográficos
Main Authors: Pudlik, Agata M., Lolkema, Juke S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426677/
https://ncbi.nlm.nih.gov/pubmed/22798354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01811-12
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