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Rerouting Citrate Metabolism in Lactococcus lactis to Citrate-Driven Transamination
Oxaloacetate is an intermediate of the citrate fermentation pathway that accumulates in the cytoplasm of Lactococcus lactis ILCitM(pFL3) at a high concentration due to the inactivation of oxaloacetate decarboxylase. An excess of toxic oxaloacetate is excreted into the medium in exchange for citrate...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3426677/ https://ncbi.nlm.nih.gov/pubmed/22798354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01811-12 |
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