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TGF-β is responsible for NK cell immaturity during ontogeny and increased susceptibility to infection during mouse infancy
A major gap in our understanding of infant immunity is why natural killer (NK) cellresponses are deficient, making infants more prone to viral infection. Here we demonstrate that transforming growth factor-β (TGF-β) was responsible for NK cell immaturity during infancy. Higher numbers of fully matur...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3426626/ https://ncbi.nlm.nih.gov/pubmed/22863752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2388 |
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