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SLX-1 Is Required for Maintaining Genomic Integrity and Promoting Meiotic Noncrossovers in the Caenorhabditis elegans Germline

Although the SLX4 complex, which includes structure-specific nucleases such as XPF, MUS81, and SLX1, plays important roles in the repair of several kinds of DNA damage, the function of SLX1 in the germline remains unknown. Here we characterized the endonuclease activities of the Caenorhabditis elega...

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Detalhes bibliográficos
Main Authors: Saito, Takamune T., Mohideen, Firaz, Meyer, Katherine, Harper, J. Wade, Colaiácovo, Monica P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426554/
https://ncbi.nlm.nih.gov/pubmed/22927825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002888
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